ERBB2 p.V777M Reference Standard
CBP10273
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| Introduction | |
| Format | Genomic DNA |
| Description | ERBB2 (HER2) V777M lies within the protein kinase domain of the Erbb2 (Her2) protein (UniProt.org). V777M has been identified in the scientific literature (PMID: 22761469, PMID: 28481359, PMID: 27284958), but has not been biochemically characterized and therefore, its effect on Erbb2 (Her2) protein function is unknown (PubMed, Sep 2018). |
| Technical Data | |
| DNA Change | c.2329G>A |
| AA Change | p.V777M |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50.00% |
| Transcript | ENST00000269571 |
| Cosmic ID | COSM14064 |
| Chr position(GRCh37) | chr17:37881000 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
